TPMs have several additional features that enhance its tumor selectivity, promote its penetration into peritoneal tumors, reduce its host toxicity and provide rapid onset, as well as sustained ...

New in vivo evidence confirms that tumor-expressed Fas ligand impairs immune responses to cancer by inducing apoptosis ... FasL when grown in the peritoneal cavity of syngeneic mice, and that ...

18 with high-grade colon and appendiceal cancer with peritoneal metastasis, and with 13 oligo-metastatic colon cancer. The funding for this investigator-initiated trial was provided by the KU ...

one in non-small cell lung cancer (NSCLC) and a second in ovarian, peritoneal, and fallopian tube cancers. Eisai, meanwhile, is running a trio of phase 1/2 trials in solid tumours. The drug is ...