The 49ers announced that DL Evan Anderson and S Jaylen Mahoney have been activated from the team's practice squad ahead of "Thursday Night Football." The San Francisco 49ers ...

Left tackle Trent Williams (toe) and safety Talanoa Hufanga (ankle) were surprise additions to the 49ers’ injury report Friday, as each missed practice. Both are questionable for Sunday’s game ...

Kyle Shanahan was named the 20th head coach of the San Francisco 49ers on February 6, 2017. Shanahan signed a multi-year contract extension with the 49ers on June 15, 2020. Shanahan and the 2022 ...

SANTA CLARA -- Even after all the success the San Francisco 49ers had the past few seasons, a two-game skid and a string of injuries early in the season can raise some doubts for any team.

Apparently, Brandon Aiyuk's $120 million extension isn't enough to keep him happy. The 49ers wide receiver, who has woefully underperformed through the season's first three weeks, let his ...

The New England Patriots just can't seem to catch a break lately, and trend appears to be continuing as they head into their Week 4 matchup with the San Francisco 49ers. While the Patriots may be ...

The San Francisco 49ers departed their win against the New ... He was seen on the sideline in a helmet and testing the ankle to open the third quarter but did not return. After the game, Warner ...

Deebo Samuel missed most of the 49ers' 28-18 loss to the Kansas City Chiefs with an illness that technically is pneumonia according to head coach Kyle Shanahan. Which means Samuel has fluid in his ...

The 49ers piled up 431 yards of offense and two touchdowns, their defense collected three turnovers — including Fred Warner’s 45-yard interception returned for a touchdown in the second ...

The 49ers are trying to stave off the dreaded Super Bowl hangover and have gotten off to a 1-2 start, and now video has emerged of head coach Kyle Shanahan confronting star wideout Brandon Aiyuk ...

Deebo Samuel was projected miss multiple weeks with a calf injury that forced him out of the San Francisco 49ers game in Week 3 against the Los Angeles Rams. But now, it’s looking like a ...