RevIT AAV Enhancer increased genome titers 1.7- to 2.2-fold with other transfection reagents compared to their respective controls, demonstrating broad applicability. Figure 1.

This schematic shows the steps involved in generating recombinant AAV by the triple-transfection method using plasmid DNA. The application of the cell-based qPCR assay at SK pharmteco has proven ...

But the triple transfection of the required plasmids, and in the strict stoichiometries required for AAV assembly, we believe adds enormously to the cost of traditional AAV manufacturing, limiting ...

In this talk, we present optimization strategies for the transfection step of vector production to generate high titers of both AAV and LV using TransIT-VirusGEN® Transfection Reagent. The VirusGEN® ...

Mirus Bio offers an innovative transfection formulation, TransIT-VirusGEN®, for high titer manufacture of both recombinant LV and AAV in adherent or suspension 293-derived cell types. In addition, our ...

Fig 1. Vector genome maps for plasmids used in the AAV triple plasmid transfection assay. AAV, adeno-associated viruses; eGFP, enhanced green fluorescent protein; GOI, gene of interest; ITR ...

TruStable™ production cell line produced ~15-fold more AAV with ~3-fold higher packaging percentage than the comparator triple transfection system, resulting in ~30-fold more material generated ...

Agathos records first sale of recombinant adeno-associated virus produced using AE1-BHK to collaborator Genovac; provides free access to AE1-BHK cell line ...