OBP-301 is a novel attenuated type 5 adenovirus that utilizes the hTERT promoter to enhance the expression of the adenovirus early in areas linked to an internal ribosome entry site (IRES) sequence.

2-[2-Benzoylamino)benzoylamino]benzoic acid (1) was previously identified as a potent and nontoxic antiadenoviral compound (Antimicrob. Agents Chemother. 2010, 54, 3871). Here, the potency of 1 was ...

Background/aims: Replication deficient adenovirus is an efficient vector for gene transfer to the cornea. The aim was to optimise the transduction of human corneal endothelium with adenoviral vectors ...

Amid White House claims of a research ‘replication crisis,’ scientists offer solutions Efforts have been underway for years to improve the replicability of research studies, but some are ...

The Collection “DNA Replication and Replication Stress” brings together original research articles, critical reviews, and perspectives from scientists with diverse viewpoints and areas of ...

Adenovirus Type 3 is commonly associated with pharyngitis, pharyngoconjunctivitis and fever, and infections with this organism may also produce vomiting, diarrhea, otitis media, transient ...

A recombinant plasmid from which an infectious adeno-associated virus genome can be excised in vitro and its use to study viral replication. J. Virol. 61, 3096–3101 (1987).

The replication-competent Ad5-Δ24 adenovirus was provided by J. F. (The University of Texas M. D. Anderson Cancer Center,Houston, TX). This virus contains a 24-nucleotide deletion, from Ad5 bp 923 to ...