Background Adipose tissue-derived stem cells (ADSCs), a type of mesenchymal stem cells (MSCs), have great potential as therapeutic agents in regenerative medicine. Numerous animal studies have ...

The fascial system builds a three-dimensional continuum of soft, collagen-containing, loose and dense fibrous connective tissue that permeates the body and enables all body systems to operate in an ...

Other connective-tissue disorders. This heterogeneous group of 21 patients included 6 with rheumatoid arthritis, 4 with dermatomyositis, 3 with Sjögren's syndrome and 1 each with polyarteritis ...

Background:In obesity and type 2 diabetes mellitus (T2D), adipose tissue expansion (because of larger adipocytes) results in reduced microvascular density which is thought to lead to adipocyte hypoxia ...

Disruption of circadian rhythms is a significant risk factor for cardiovascular diseases, yet the underlying mechanisms remain incompletely elucidated. BMAL1, a core component of the circadian clock, ...

Background Epicardial adipose tissue represents a metabolically active visceral fat depot that is in direct contact with the left ventricular myocardium. While it is associated with coronary artery ...

CHARLOTTESVILLE, Va. (WVIR) - UVA Health is launching a new, national program that will target connective tissue disorders, a development that doctors say is sorely needed. Thanks in part to a $3 ...

Figure 1. Pathways linking local obesity-induced inflammation to systemic insulin resistance. Obesity results in the activation of the inflammatory signaling pathways mediated by JNK and nuclear ...

Extracellular vesicles have emerged as promising tools in regenerative medicine due to their inherent ability to facilitate intercellular communication and modulate cellular functions. These nanosized ...