Apoaequorin, the main ingredient in Prevagen, is an over-the-counter dietary supplement. Find out what's in it, what the possible side effects are, and more. Skip to main content ...

Key Features. Apoaequorin, the main ingredient in Prevagen, is a calcium-binding protein originally found in jellyfish, but the supplement features a lab-manufactured synthetic version of this ...

In nature, apoaequorin produces a blue light when exposed to calcium. Apoaequorin is thought to help improve memory and slow progressive loss of cognitive function, but little evidence supports this.

Apoaequorin has no known role in human memory. (And as a snarky aside, I might note that jellyfish are not known for their mental acuity.) Research has failed to show that apoaequorin improves ...