We are at an inflection point that is driving a renaissance in antibody-drug conjugate (ADC) development. As successes in the clinic have led to more U.S. Food & Drug Administration (FDA) approvals, ...

Conjugated polymers are organic macromolecules that are characterized by a backbone chain of alternating double- and single-bonds. Their overlapping p-orbitals create a system of delocalised π ...

Promising ADC Efficacy in Resistant Ovarian Cancer: Lilly’s investigational FRα-targeting ADC, LY4170156, showed a 55% response rate at the proposed Phase II dose in platinum-resistant ovarian cancer, ...

In-line optical phase conjugation is a well-known technique to enhance the received signal quality through nonlinearity compensation. Being able to implement the conjugation in cm-scale highly ...

Two high molecular weight conjugated polymers (CPs), i.e., poly [N,N′ -bis (4-tetradecyloctadecyl)-7,7′-difluoroisoindigo- alt -2,2′-bithiazole] (P2FI2Tz) and poly [N,N′ -bis (4-tetradecyloctadecyl)-5 ...

This paper aims to identify the current state of the art of the latest research related to Conjugate Gradient (CG) methods for unconstrained optimization through a systematic literature review ...

About Cynaptec Pharmaceuticals, Inc. - Cynaptec is a biopharmaceutical company dedicated to developing innovative therapies for neurological and psychiatric disorders. Cynaptec's initial development ...

Developing efficient adsorbents for uranium enrichment is of great significance for resource sustainability and environmental safety. This study presents a facile and adaptable post-synthetic strategy ...

The serum levels of conjugates of chenodeoxycholic acid (chenyl conjugates) and of cholic acid (cholyl conjugates) were determined by specific radioimmunoassays during a 24-hour period, which included ...