Nanoparticles (NPs) are materials whose dimensions range from 1 to 1,000 nanometers (nm). Due to their nano-scale dimensions ...

Nanoparticles (NPs), materials with sizes ranging from 10 to 1,000 nm, are increasingly utilized as drug-delivery systems and ...

Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune ...

New research by Sumeda Nandadasa, Ph.D., reveals how a key protein associated with Meckel-Gruber syndrome, nephronophthisis, ...

A new way to grow stem cells may help them release more of the signaling proteins they use to repair tissue, potentially ...

When Alphabet announced in 2021 that its AlphaFold AI could predict the structure of almost every known protein, it was a major story, not just in the pharma world, but beyond.

The latest version of Google DeepMind and Isomorphic Labs’ AlphaFold model can predict the structure and relationships not only of proteins, but “all of life’s molecules”, according to its ...

Drug discovery is the process through which potential new medicines are identified. It involves a wide range of scientific disciplines, including biology, chemistry and pharmacology. A randomized ...

Machine learning methods are widely used in bioinformatics and computational and systems biology. Here, we review the development of machine learning methods for protein structure prediction, one of ...

Employing first principles calculations, we examined doped and imperfect ZnO sheets to reveal the electronic structure properties. We mainly investigated the imperfect sheets arising from the host ...

Molecular replacement in X-ray crystallography is the prime method for establishing structure–activity relationships of pharmaceutically relevant molecules. Such an approach is not available for NMR.