Scientists also showed that, for the blood-brain barrier surrounding the mice cerebellum -- a region responsible for muscle coordination -- L6-F4-2 replaced Norrin and activated WNT signaling.

By getting drugs beyond the blood-brain barrier, researchers believe they could better target treatment for Alzheimer’s disease, seizures, and plenty more. So, it’s safe to say it’s been a goal.

Post-Covid "brain fog" could be caused by leaky blood vessels in the brain, a groundbreaking new study out of Ireland has determined. Researchers from Trinity College Dublin recruited 32 patients ...

The brain is among the most “immune-privileged” of organs primarily through the highly selective permeability of the blood-brain-barrier (BBB), its minimal lymphatic drainage, the presence of ...

Powerful chemotherapy drugs have reached deadly brain tumours for the first time after scientists worked out how to open the blood-brain barrier. In a major breakthrough in the treatment of brain ...

The blood-brain barrier performs a vital function in keeping out toxins and pathogens, but it can become “leaky.” Now Stanford scientists have identified therapeutic molecules that could help ...

A new drug targeting inflammation in the brain has been shown to bolster the blood-brain barrier in mice, pioneering a potential shift in the fight against neurodegenerative diseases like Alzheimer's.

"Our study shows that these blood-brain barrier-crossing lipid nanoparticles (BLNPs) can safely and efficiently deliver mRNA ...

Blood–brain barrier articles from across Nature Portfolio. Atom; RSS Feed; Definition. The blood–brain barrier acts as a strict control point for what can enter the brain, and is created by ...

Scientists Find Way to Deliver Medicines Across Brain's Protective Barrier By Dennis Thompson HealthDay Reporter WEDNESDAY, Nov. 27, 2024 (HealthDay News) -- The blood-brain barrier is a natural ...

Researchers have found an antibody that disrupts this blood-brain barrier in some people with an autoimmune disease (Sci. Transl. Med. 2017, DOI: 10.1126/scitranslmed.aai9111).