Increased width of the CSP has been reported in cases with chromosomal abnormalities, including trisomy 13, 18 and 21, and microdeletion 22q11, and with neurodevelopmental delay. 1 12 15–18 Of note, ...

The main exposure was twin pregnancy. All pregnant women in Norway are offered routine second-trimester ultrasound examination free of charge, and 99% of women undergo this examination, during which ...