Researchers at Leipzig University's Carl Ludwig Institute have discovered that in the cerebral cortex, synaptic signal ...

When the signal reaches the axon terminals, the electrical charge changes once more: instead of sodium ions, it is the positively charged calcium ions that enter the extra-permeable cell membrane.

When an axon fires, voltage-sensitive ion channels in the neuron's membrane open, allowing calcium ions to enter. We would therefore expect to see the firing as a flash of green fluorescence ...

Axon branching connects single neurons with multiple targets, which, along with the formation of highly branched terminal arbors, underlies the complex circuitry of the vertebrate CNS. Axon ...

The two receptors -- RyR3 and IP 3 R --are each associated with a different kind of calcium release from the endoplasmic reticulum, and with axon growth toward attractive signals. Kamiguchi explains, ...

The AP travels down the axon towards the axon terminal, where it signals to other neurons via the synapse. The ion fluxes during APs dissipate ion gradients, and energy is needed to re-establish ...

Because the lysosomes did not refill with calcium, either, the authors concluded that the ER was the source of these ions. To directly test whether CTFs are involved in lysosomal Ca 2+ flux, the ...

Jan. 29, 2024 — Calcium ions are essential for cells, but can be toxic in higher concentrations. A team of researchers has now designed and prepared a combination drug that kills tumor cells by ...

If an attractive signal is on the left, new pieces of axon membrane are inserted into the left side of the growth cone, which makes the axon grow towards the attractive signal. Until now, while ...