Treating mice that had the CB1 receptor with an endocannabinoid agonist resulted in a decline in polyps ranging from 16.7 percent to 50 percent. The reduction was greater for larger polyps.

A Chinese research team joined forces with Russian and U.S. biologists to obtain the crystal structure of the human type 2 cannabinoid receptor. Their findings will help develop drugs against ...

Like the body’s own endocannabinoids, CBN interacts with the ECS by binding to cannabinoid receptors, which are primarily found in the central nervous system, as well as in immune cells.

Since cannabinoid receptor agonists vary by how much they interact with the standard or proposed non-CB 1 and non-CB 2 targets, it follows that certain ligands that activate CB 1 and/or CB 2 ...

A recent review of research on cannabinoid receptors and their influence on signaling pathways provides insights into how the endocannabinoid system boost energy, stimulates appetite, reduces pressure ...

A recent study describes the success of using lenabasum, a cannabinoid receptor type 2 (CB2) agonist that triggers the resolution of inflammation, to treat amyopathic dermatomyositis. This phase 2 ...

The CB1 receptor is found in the brain and nervous system and is the main receptor for THC and anandamide. The receptor found in the immune system and surrounding structures is CB2, which is ...

The researchers also administered the synthetic CB1 receptor agonist CP 55,940. They found that the 0.06-mg/kg dose had a similar effect on body weight, food intake, and daily RWA.

HOUSTON - New preclinical research shows that cannabinoid cell surface receptor CB1 plays a tumor-suppressing role in human colorectal cancer, scientists report in the Aug. 1 edition of the ...

The endocannabinoid system is an active and complex cell signaling network. It involves a combination of endocannabinoids, enzymes, and cannabinoid receptors that help regulate several functions ...

Anandamide behaves as a partial agonist of cannabinoid receptors with slightly greater CB1 than CB2 affinity, but with much lower CB2 than CB1 efficacy.Other endocannabinoids (such as arachidonyl ...