Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Tumor associated macrophages (TAMs) are pivotal in the tumor microenvironment, influencing angiogenesis, metastasis, and immunosuppression. This study explores macrophage polarization using a ...

In vitro (macrophages, endothelial cells, skeletal muscle cells under normal and hypoxia serum starvation conditions) and in vivo experiments in preclinical PAD models (unilateral femoral artery ...

Macrophage polarization between pro-inflammatory M1 and anti inflammatory M2 phenotypes significantly influences inflammation and tissue repair. This study evaluates the effect of the secretome from ...

Although previous studies have reported the potential of nanotechnology-based approaches to guide macrophage polarization through reactive oxygen species (ROS) clearance, we still opted for periodic ...

Macrophages, including BMDMs, can function across a spectrum from being pro-inflammatory (M1) to anti-inflammatory (M2). (13,14) These shifts in function can be distinguished by changes in gene ...

This review aims to elucidate how different macrophage polarization phenotypes influence the progression of atherosclerosis while also exploring the significance of m6A modifications in this ...

Macrophages are present in all body compartments, including cancerous tissues, and their functions are profoundly affected by signals from the microenvironment under homeostatic and pathological ...