Disabling mERα in female mice reduced cortical bone mass, the dense outer layer of bones that provides strength and ...

A new study by Rice University researchers led by Jason Hafner could open new pathways for understanding how cholesterol ...

Study identifies proximity-based mechanism behind LAG-3 inhibition and introduces novel bispecific antibody for autoimmune ...

Taste, pain, or response to stress—nearly all essential functions in the human body are regulated by molecular switches called G protein-coupled receptors (GPCRs). Researchers at the University ...

Chimeric antigen receptor (CAR) on T-cell, illustration. The CAR structures are blue, with the cutaway foreground showing one spanning the cell membrane.

Data from the Web of Science (ISI, Philadelphia) show that Hot Papers are cited 50 to 100 times more often than the average paper of the same type and age. M. Razandi, A. Pedram, G.L. Greene, E.R.

Alterations in thyroid gland function result from the action of stimulating or blocking autoantibodies on cell membrane receptors. Three principal thyroid autoantigens are involved in AITD.

This study employed high-throughput screening and animal models to identify FPR2, a G protein-coupled receptor (GPCR) expressed at the adipocyte plasma membrane, as a critical ceramide receptor.

Superluminal focuses on G protein-coupled receptors (GPCRs), which are proteins embedded in the membranes of cells. Cells use membrane receptors to communicate with each other and detect changes ...

The GIP receptor activates futile calcium cycling in white adipose tissue to increase energy expenditure and drive weight loss in mice. Cell Metab. 2025;37(1):187-204.e7. Sharma AK, et al. Futile ...