Disabling mERα in female mice reduced cortical bone mass, the dense outer layer of bones that provides strength and ...

Scientists have discovered novel drug candidates which could ultimately lead to new effective treatments for conditions ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

Study identifies proximity-based mechanism behind LAG-3 inhibition and introduces novel bispecific antibody for autoimmune ...

Aussie researchers have used CRISPR gene editing tools to “armor” chimeric antigen receptor (CAR) T cells to activate additional cancer-fighting proteins at the tumor site, enabling them to target ...

Cell-to-cell communication (CCC) plays important roles in multicellular organisms. The identification of communication between cancer cells themselves and one between cancer cells and normal cells in ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living ...

TfR was the first receptor to be identified, it is glycosylphosphatidylinositol (GPI)-anchored and has been localised to the flagellar pocket and endosomal membrane in some studies but others ...

Membrane receptors, particularly G protein-coupled receptors (GPCRs), are integral to numerous physiological processes. Precise control of the receptor endocytosis is essential for understanding ...

Receptor–ligand interactions on cell membrane play key roles in many physiological and pathological processes, especially in the nanodrug targeted delivery system. Hyaluronic acid (HA) is the main ...