Disabling mERα in female mice reduced cortical bone mass, the dense outer layer of bones that provides strength and ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

Study identifies proximity-based mechanism behind LAG-3 inhibition and introduces novel bispecific antibody for autoimmune ...

Aussie researchers have used CRISPR gene editing tools to “armor” chimeric antigen receptor (CAR) T cells to activate additional cancer-fighting proteins at the tumor site, enabling them to target ...

Cornell researchers have found a new and potentially more accurate way to see what proteins are doing inside living ...

Public Reviews: Reviewer #1 (Public review): Unfortunately, the revised manuscript does not show significant improvement. While the identification of the receptors is highly convincing, important ...

Chimeric antigen receptor (CAR) on T-cell, illustration. The CAR structures are blue, with the cutaway foreground showing one spanning the cell membrane.

To address this gap in knowledge, we aimed to identify the potential cell membrane receptor for CTRP9 by analyzing the interaction between CTRP9 and three candidate receptors, namely Cadherin-13, ...

G protein-coupled receptors (GPCRs) are the largest and most diverse group of membrane receptors in the body. They are responsible for many physiological responses in the body and are attractive drug ...

Lilly-backed Superluminal raises $120M series A to bring membrane receptor drugs into the clinic By Darren Incorvaia Sep 9, 2024 7:00am G protein-coupled receptors Eli Lilly series A GPCR ...

On-demand engineering of cell membrane receptors to nongenetically intervene in cellular behaviors is still a challenge. Herein, a membraneless enzyme biofuel cell-based self-powered biosensor ...

Collaboration between a cis-interacting natural killer cell receptor and membrane sphingolipid is critical for the phagocyte function Hitomi Karyu 1 Takahiro Niki 2 Yuriko Sorimachi 3,4 Shoji Hata 5 ...