Collagen IV provides crucial structural support for cells and tissues, but it’s unstable at body temperature. Researchers now ...

A new study by University of Bath scientists has highlighted two new potential families of drug molecules that could open the ...

Here we use cryogenic electron microscopy to determine the structure of TbAQP2 from Trypanosoma brucei, bound to either the substrate glycerol or to the sleeping sickness drugs, pentamidine or ...

Understanding how molecular arrangements within crystals influence their thermal behavior is a fundamental question in ...

Polydiacetylenes (PDAs) possess dramatic chromatic transitions, which can be exploited to make stimuli-responsive sensors. Key to developing robust sensors is understanding the changes in molecular ...

News & Views Published: October 2005 Decoding chemical structures from genomes Brian O Bachmann Nature Chemical Biology 1, 244–245 (2005) Cite this article ...

ATAD2 (ANCCA) is an epigenetic regulator and transcriptional cofactor, whose overexpression has been linked to the progress of various cancer types. Here, we report a DNA-encoded library screen ...

The model’s predecessor, Boltz-1, was released last November as the first fully open-source model to achieve AlphaFold 3-level accuracy in predicting the 3D structure of biomolecular complexes ...