While organoids aim to mimic human organs, the liver's repertoire of complex functions – and thus the energy it needs to operate – have made it challenging for researchers to grow organoids that ...

Scientists achieve breakthrough in liver research with mini organoids that grow a million-fold and stay functional for months.

The liver is the body's control tower for metabolism, powering vital functions like converting nutrients to glucose, storing fat and breaking down toxins. Over a third of the world, however, is ...

When prioritizing growth and survival in laboratory settings, hepatocytes, the liver’s main cells, eventually transformed into cells resembling cholangiocytes, which line the bile duct.

Through multi-modal data integration, we define molecular signatures driving cell state transitions in liver disease and define an impaired cellular response and directional trajectory between ...