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Nature21y
Osteogenic potential of five different recombinant human bone morphogenetic protein adenoviral vectors in the rat | Gene Therapy - Nature
The average volume of new bone induced by 107 PFU of BMP vector in athymic nude rats was 0.37±0.03 cm3 for ADCMVBMP-2, 0.89±0.07 cm3 for ADCMVBMP-4, 1.02±0 ...
Nature18y
Delayed administration of adenoviral BMP-2 vector improves the formation of bone in osseous defects | Gene Therapy - Nature
The direct, local, administration of adenovirus carrying human BMP-2 cDNA (Ad.BMP-2) heals critical-sized femoral bone defects in rabbit and rat models. However, the outcome is suboptimal and the ...