The actin cytoskeleton plays crucial roles in many cellular processes, including regulated secretion. However, the mechanisms controlling F-actin dynamics in this process are largely unknown.

In secretory cells, exocytosis and compensatory endocytosis are tightly coupled membrane trafficking processes that control the surface area and composition of the plasma membrane. While exocytic ...

The gene discovered in the research couples the exocytosis-regulating protein Sec10 with formin, a protein that regulates the remodeling of the actin cytoskeleton critical to forming cell shapes.

(May 8, 2019) – Dysfunctions and malformations in the scaffold of a cell are thought to contribute to heart muscle weakness, neurodegenerative disease and even deafness.Now biophysics research at The ...

Endocytosis, Adhesions and Cytoskeleton. Curved and flat clathrin structures in health and disease Approximately 15% of the proteins produced in our bodies are destined for the surface of our cells.

ROCKVILLE, MD – The Biophysical Society is pleased to announce that Hugo Lachuer, PhD, of the Institut Jacques Monod (CNRS) and Nadab Wubshet, PhD, of the University of Michigan and Harvard ...