Tiny fat bubbles carrying gene therapy have successfully repaired DNA in the lungs and liver of animals with alpha-1 antitrypsin deficiency — a promising leap toward treating humans with this rare ...

He and a colleague proved a theory advanced by the Nobel Prize winners James Watson and Francis Crick, who discovered DNA’s ...

Origin activity in log cultures is typically assessed by comparing replication initiation within an origin, presenting as a bubble arc, to passively replicated DNA (Y-arc).

When it comes to DNA replication, humans and baker's yeast are more alike than different Date: August 1, 2024 Source: Van Andel Research Institute Summary: Humans and baker's yeast have more in ...

Bubble-seq (Mesner et al., 2013) generates long reads because it captures the origin-containing replication intermediates by selection of DNA bubbles, and so may enrich origins that are flanked by ...

DNA melting bubbles are the basis of many DNA-protein interactions, such as those in regulatory DNA regions driving gene expression, DNA replication and bacterial horizontal gene transfer. Bubble ...

DNA replication is required to maintain the integrity of genomic information. This article describes the process of DNA replication, in a step-by-step manner.

Each replication bubble has two replication forks moving in opposite directions. As the replication bubbles progress along the DNA molecule, they eventually fuse, resulting in two complete and ...

At first, that frothy stream of carbonation seems endless. But just how many bubbles can emerge from a glass of beer before it goes flat? Gérard Liger-Belair, a professor of chemical physics at ...

The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell ...