In vivo base editing enables precise, single-nucleotide changes to DNA without double-strand breaks. A recent application in ...

Kiwis can boost your gut health. They may also lower triglycerides and cancer risk. Is there something I can eat to help with ...

The collapse of DNA replication forks leads to the formation of single-ended DNA double-strand breaks. One would have assumed that these breaks would be repaired as soon as possible.

While it is accepted that extracellular vesicles (EVs)-mediated transfer of microRNAs contributes to intercellular communication, the knowledge about molecular mechanisms controlling the selective and ...

Scientists with the NIH-backed SMaHT Network are mapping every DNA mutation in the human body, creating a groundbreaking ...

From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's ...

A deeper understanding of how DNA changes over generations helps scientists learn why people differ and how diseases develop.

The discovery may explain why cutting edge CAR T-cell therapy has managed to revolutionized treatment for blood cancer but ...

Fourteen million people worldwide suffer from enlarged hearts, or hypertrophic cardiomyopathy (HCM), a genetic disease that ...

Researchers working on an incurable blood cancer can now use a new lab model that could make testing potential new treatments ...

Study results advance understanding of how human cells evolved and could help point to new solutions for patients with rare genetic diseases.