More information: Saroj K. Rout et al, Amino acids catalyse RNA formation under ambient alkaline conditions, Nature Communications (2025). DOI: 10.1038/s41467-025-60359-3.

Amino acids can catalyze RNA polymerization under mild, prebiotic conditions, increasing RNA formation by up to 100-fold through acid-base catalysis involving their amine groups.

Reducing our intake of a single amino acid called methionine, which we get from the food we eat, could help protect against ...

Natural nucleic acids like DNA and RNA have a sugar-phosphate "backbone" and nitrogen-based components; while the nitrogen-based components in SNA and L-aTNA remain the same, they have an amino ...

Results of a new study published in the journal Science on Jan. 2 shows for the first time that amino acids, known as the building blocks of protein, can be assembled without DNA and messenger RNA ...

Sugar: In DNA, the sugar is deoxyribose, while in RNA, it is ribose.The sugar forms the backbone of the nucleic acid strand. Phosphate Group: The phosphate group is attached to the sugar and helps ...

These lab-made molecules can bind to genes more strongly than DNA and RNA do, ... But unlike DNA, their backbones are made from amino acids rather than sugar phosphates.

Accurate measurement of DNA or RNA concentration and purity is fundamental for many downstream processes, including transfection, electroporation, cloning, PCR and NGS. 1, 2 Without proper ...

The latest issue of Science features a paper 1 on synthetic nucleic acids, completely new molecules capable of information storage just like DNA and RNA, dubbed xeno-nucleic acids, or XNAs.

At an alkaline pH, amino acids exist in both neutral and negatively charged forms, enabling them to shuttle protons in the polymerization reaction that forms RNA from ribonucleoside 2′,3 ...