Vaccines using mRNA are currently being studied for a wide range of diseases, including cancer, cardiovascular disease, ...

Punishing conditions in the clouds of Venus could be home to a DNA-like molecule capable of forming genes in life very ...

An elegant screening strategy unveils a molecular actor that connects widespread changes in mRNA processing with a nutrient-sensing protein modification.

The mitochondrial genome can help researchers map ancestry and better understand the inheritance of mitochondrial diseases.

Viruses are known to use the genetic machinery of the human cells they invade to make copies of themselves. As part of the process, viruses leave behind remnants throughout the genetic material ...

Clinical trial of KH658 evaluates single suprachoroidal space administration of gene-therapy treatment for wet AMD ...

"In the small molecule era, it was critical to control the placement of every atom and every bond within a particular ...

The RNA cloud formed around genes regulates their readout into RNA. Triplexes help define where in the genome a cloud forms. Proteins and other fl ...

Fifty years since its discovery, scientists have finally worked out how a molecular machine found in mitochondria allows us to make the fuel we need from sugars, a process vital to all life on Earth.

NGS is a cornerstone of modern biotechnology, enabling rapid and cost-effective DNA and RNA sequencing that supports important advances in cancer research, drug development, agricultural ...

Papers in this issue focus on original research offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches.