A phase 3 trial shows that once-weekly semaglutide significantly improves liver histology in patients with metabolic dysfunction-associated steatohepatitis (MASH). The interim results also reveal ...

and povetacicept for IgA nephropathy. Vertex is also evaluating zimislecel in late-stage testing as a potential cure for several kinds of type 1 diabetes. Maybe some of these candidates will be ...

According to a study published in Nutrition & Diabetes, regular use of glucosamine, a supplement often taken for joint pain, may reduce the risk of microvascular complications, including diabetic ...

The funds will be used to support the advancement of the Chicago biotech’s myasthenia gravis (MG) and type 1 diabetes (T1D ... of concept trial in cystic fibrosis for ETD001, an ENaC blocker ...

Aldosterone has been shown to cause coronary inflammation, cardiac hypertrophy, myocardial fibrosis ... can be induced by renal insufficiency, diabetes mellitus, advanced heart failure, advanced ...

Diabetic kidney disease ... pathophysiology of DKD - The role of inflammation in the pathophysiology of DKD - The role of fibrosis in the pathophysiology of DKD - Renoprotective effects of ...

MASH is a progressive liver disease characterised by inflammation and fibrosis and is closely linked to obesity and Type 2 diabetes. In a significant interim analysis from a large, phase 3 clinical ...

He had well-controlled diabetes but no history of kidney disease ... Mild glomerular changes consistent with diabetic and hypertensive nephropathy. Mild Interstitial fibrosis and tubular atrophy. Mild ...

In sum, NPH has morphological presentation characterized by hypoplastic kidneys, increased inflammation and fibrosis and cortico-medullary ... in line with the high frequency of obesity and type 2 ...