Objectives Cognitive flexibility, which is key for adaptive decision-making, engages prefrontal cortex (PFC)-striatal circuitry and is impaired in both manifest and premanifest Huntington’s disease ...

Summary: A new study has examined brains affected by PTSD at the single-cell level, uncovering distinct genetic alterations that may drive the disorder. Researchers focused on the dorsolateral ...

"The dorsolateral prefrontal cortex has been very well studied," says Girgenti. "But there are other regions of the brain that we know a lot less about, and they're just as likely to hold secrets ...

The prefrontal cortex is a cortical area located in the anterior frontal lobe, including several subdivisions (e.g. ventromedial, dorsolateral, orbitofrontal cortices).