The researchers from the TalTech molecular neurobiology laboratory headed by professor Tõnis Timmusk used the fruit fly, Drosophila melanogaster to develop a novel disease model for Pitt-Hopkins ...

Drosophila effectively models human genes responsible for genetic kidney diseases Assessing the function of human monogenic podocyte mutations that cause nephrotic syndrome Date: March 17, 2017 ...

A mutant allele derived from a patient with CD2AP-associated NS did not rescue the phenotypes. Video: Using the Drosophila model to learn more about disease in humans ...

Researchers at Tohoku University have discovered that an oral drug called MA-5 can improve both heart and muscle problems in ...

The common fruit fly (Drosophila melanogaster), more correctly called the vinegar fly, is a frequent visitor to ripe fruit in households around the world, where it often deposits eggs on rotting flesh ...

Researchers developed an iPSC-derived peripheral myelination model, advancing research into rare diseases impacting the PNS and potential treatments.

The genetic architecture of human disease is often hard to replicate in model organisms, and disease modelling in human cells is rapidly improving. Six leading model organism researchers provide ...

Research uncovered how glycogen metabolism in neurons impacts neurodegenerative diseases like Alzheimer's. Disruption in this sugar breakdown leads to oxidative stress and cell damage.

Paraneoplastic syndromes are a group of disorders associated with tumors that are prevalent in patients with lymphatic, lung, ovarian or breast cancers.

New human cell-based 3D model reveals insights into how immune cells contribute to Alzheimer's disease The model provides insights into the progression of AD and could help to accelerate the ...

This paper takes us from very fundamental cell biology in a fly, to explaining a human disease and harnessing that knowledge for a cancer therapy.