A wide variety of animals have been previously used in animal testing, including mice, flies, and monkeys. A particularly useful model organism is Drosophila melanogaster, commonly known as the ...

The researchers from the TalTech molecular neurobiology laboratory headed by professor Tõnis Timmusk used the fruit fly, Drosophila melanogaster to develop a novel disease model for Pitt-Hopkins ...

Compared to mammalian model systems,Drosophila offers the power of rapid and high-throughput genetic analysis, with a generation time ten times faster than the mouse. Further, fly models have now been ...

A Drosophila model system to assess the function of human monogenic podocyte mutations that cause nephrotic syndrome. Human Molecular Genetics , 2017; 26 (4): 768 DOI: 10.1093/hmg/ddw428 Cite This ...

This fly model shows a gradual increase in the number of α-synuclein-containing inclusion bodies, and this was unaltered in flies also expressing Hsp70. In addition, Drosophila Hsp70 was found in the ...

In a newly described Drosophila model, two of the five antiepileptic drugs (AEDs) tested, sodium valproate (NaVP) and levetiracetam (LEV), not ethosuximide (ETH), gabapentin (GBP) and vigabatrin ...

By utilizing a well-established Drosophila midgut model for stem cell aging biology, the researchers revealed that vitamin D receptor knockdown in ECs induced ISC proliferation, EC death, ISC ...

Gliomas are the most common brain tumors. Adult gliomas frequently present molecular alterations in the epidermal growth factor receptor (EGFR) and its associated signaling pathways. In recent work, ...