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Dulanto Chiang and Dekker discuss recent work on efflux pump-mediated antibiotic resistance in gram-negative bacteria.

Well-known examples of efflux pumps are P-glycoprotein (P-gp) 51, 52, 53 and breast cancer resistant protein (BCRP) 54, 55, which are expressed on the apical surfaces of the gut wall epithelium ...

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Sub-populations of non growing bacteria survive treatment with antimicrobial peptides by mounting an efflux response.

Heterogeneous expression of efflux pumps within isogenic bacterial populations has been reported 29, 32, 33, 67 – 69. However, recent reports have suggested that efflux is not the primary mechanism of ...

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Here, we revealed that Xcc exports benzoic acid, cinnamic acid, and their monohydroxylated derivatives through the resistance-nodulation-division family efflux pump HepABCD. This efflux system ...

Cell envelope plays a dual role in the life of bacteria by simultaneously protecting it from a hostile environment and facilitating access to beneficial molecules. At the heart of this ability lie the ...