The NorA efflux pump is a potential drug target for reversal of resistance to selected antibacterial agents, and recently we described indole-based inhibitor candidates. Herein we report a second ...

Antibiotic efflux pumps are expressed in all microbes, where they serve as crucial gatekeepers in resisting the cellular ...

Webber, M.A. (2002) The Importance of Efflux Pumps in Bacterial Antibiotic Resistance. Journal of Antimicrobial Chemotherapy, 51, 9-11.

More information: Jennifer C. Earp et al, Structural basis of siderophore export and drug efflux by Mycobacterium tuberculosis, Nature Communications (2025). DOI: 10.1038/s41467-025-56888-6 ...

Finding a way to disable the efflux transporters of M. tuberculosis with an inhibitor would strike a double blow — restore microbial sensitivity to antibiotic bedaquiline and break the cycle that ...

The proteins MmpL5 and MmpL4 are efflux transporters, critical pumps that help the pathogen M. tuberculosis grow by scavenging essential iron from the iron-deprived lung granulomas of its human host.

They announced the integration of FreeStyle Libre 2 Plus CGM into the t:slim X2 insulin pump in January 2024. “Integrating our advanced insulin delivery systems with Abbott’s future glucose-ketone ...

New Technologies Numerous ductless heat pump systems are now available for cold climates. These include most of Fujitsu’s AIRSTAGE H and J-Series ductless products, which meet — and often exceed — the ...