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BACKGROUND Autoimmune polyendocrine syndrome type 1 (APS-1) is a rare autosomal recessive disorder characterised by a triad of mucocutaneous candidiasis, hypoparathyroidism and primary adrenal failure ...

Patients' symptoms are often diffuse, and can include pain in the extremities, paraesthesia, fatigue and mood swings There has been a significant increase in toxic metals in brown crab meat in recent ...