This study reveals that neutrophil extracellular traps (NETs) drive macrophage-derived chemokine production (CXCL9/10/11) to promote CD8+ T cell ...

Loss of a key immune protein disrupted cell signaling and defense, revealing a novel driver of chronic airway inflammation in ...

This new article publication from Acta Pharmaceutica Sinica B, discusses targeting stem-property and vasculogenic mimicry for sensitizing paclitaxel therapy of triple-negative breast cancer by ...

Etokimab (I-Mab Biopharma), which is optimized for common IL-33 gene polymorphisms, has completed patient recruitment in its ...

Two biomarker tests -- one for blood and the other for stool -- are mainstays in the treatment of inflammatory bowel disease ...

The NOX-targeted therapy market is expected to expand significantly over the upcoming years as more therapies move into ...

At the basal (lower) side, the cytoplasm of epithelial cells spread planarly, creating a thin layer. Macrophage-like cells ...

Glucan-mediated trained immunity activates alveolar macrophages which exacerbates acute lung injury induced by LPS.

Finding ways to tackle tumour associated macrophages, part of the “tumour microenvironment” that is the focus for so many big pharma companies, is one of the goals of the ambitious biotech ...

The researchers then found that when they genetically decreased the macrophages’ ability to consume dying cancer cells, or decreased Upd3 production, tumor growth was significantly reduced.

Epithelial cells form the skin’s outer layer and line the gut, blood vessels, airways—basically “every single organ in your body that connects to the outside world,” says Ellen Foxman, who ...