This study reveals that neutrophil extracellular traps (NETs) drive macrophage-derived chemokine production (CXCL9/10/11) to promote CD8+ T cell ...

Loss of a key immune protein disrupted cell signaling and defense, revealing a novel driver of chronic airway inflammation in ...

Vienna, Austria – June 6, 2025 — Myllia Biotechnology, a pioneer in functional genomics in primary human cells, today announced a major technological breakthrough with the launch of VISTA ™ —the first ...

The increased expression of SLC31A1 promoted cuproptosis of macrophages and elevated tumor necrosis factor-α (TNF-α) secretion, which activated the NLR family pyrin domain containing 3/matrix ...

Tumor-associated macrophages (TAMs) play crucial roles in the process of epithelial–mesenchymal transition (EMT) in lung cancer. TAMs promote EMT in tumor cells by releasing cytokines and growth ...

Infection of the respiratory system by diseases like COVID-19 and flu causes damage to the epithelium. During the healing process, regenerative cells are typically kept in check by macrophages, as ...

As mice aged, macrophages in the choroid plexus secreted more cathepsin S, breaking down the blood-CSF barrier. Inhibiting cathepsin S protected the barrier and preserved memory. Senescent cells ...

M1 macrophages accumulate in non-eosinophilic chronic rhinosinusitis with nasal polyps (neCRSwNP), but their regulation and impact on the epithelial barrier remain unclear. Researchers conducted a ...

Clements, D. and Idoyaga, J. (2021) Alveolar Macrophages and Epithelial Cells The Art of Living Together. Journal of Experimental Medicine, 218, e20211583.

Deep in the brain, sheets of tissue known as the choroid plexus produce cerebrospinal fluid (CSF) and act as a protective ...

In triple-negative breast cancer, infiltrating macrophages induce an immunosuppressive effect, altering cytokine expression and fostering the expression of tumor-promoting factors in epithelial cells, ...