Myeloid-epithelial-reproductive tyrosine receptor (MerTK), a receptor on the surface of the cardiac macrophage, is key to phosphatidylserine-triggered activation and was previously shown to be ...

This study reveals that neutrophil extracellular traps (NETs) drive macrophage-derived chemokine production (CXCL9/10/11) to promote CD8+ T cell ...

Macrophages are immune cells that are found in every organ of the body. The research team, led by Thomas Weichhart of MedUni Vienna's Center for Pathobiochemistry and Genetics and coordinator of the ...

Loss of a key immune protein disrupted cell signaling and defense, revealing a novel driver of chronic airway inflammation in ...

One surprising finding from this imaging was that the infected T cells seemed to target epithelial cells directly above macrophages. "The macrophage just stays still, ready to get the virus when ...

It highlights macrophages for the first time as "metabolic factories" that support the metabolism of other cells, which is critical for efficient self-renewal of the intestinal epithelium.

image: TB bacteria infect host macrophages in a larval zebra fish and prod epithelial cells to produce MMP9, a signaling protein associated with worsening infection.

“Although alveolar epithelial cell dysfunction may initiate the development of IPF, our findings suggest that repeated epithelial cell injury is not required for the progression of fibrosis.” “We ...

The pathogen-to-epithelium-to-macrophage pathway they uncovered should provide several new avenues that could be targeted for intervention." Co-authors of the article, ...

Infection of the respiratory system by diseases like COVID-19 and flu causes damage to the epithelium. During the healing process, regenerative cells are typically kept in check by macrophages, as ...