In addition to discoveries of leptin's role in cellular fat metabolism, Kim and his colleagues also have found a way to produce longer-lasting leptin. "Native leptin produced in the body is short ...

WebMD explains what the leptin hormone is, how it affects weight, and whether leptin supplements are safe or effective.

The hormone leptin helps you feel full. You don’t get it from food, but a poor diet or extra pounds may make it less effective.

Mouse study published in Science Translational Medicine suggests an old approach to obesity, the leptin hormone, could improve efficacy of GLP-1 drugs.

The team found that rapamycin restores leptin sensitivity to diet-induced obese (DIO) mice, leading to significant loss of fat with only minimal effects on muscle.

We know that too much body fat is generally bad for our cardiovascular system, and now scientists are learning more about how too little fat yields some of the same damage.

Serum leptin concentrations significantly decreased in hyperthyroid rats after 7 and 15 days of treatment, while a significant increase was found in hypothyroid rats only after 15 days.

But FAT-ATTAC ob/ob mice, which not only have no leptin, but no fat, have only about half the normal insulin. The fatless FAT-ATTAC ob/ob mice also failed a glucose-tolerance test, indicating that ...

Leptin is a hormone that makes you feel full. Leptin was only discovered in 1994, and scientists are still working to understand what leptin's role is. In most people the function of leptin is to ...

Recombinant leptin was administered subcutaneously twice a day for four months at escalating doses to achieve low, intermediate, and high physiologic replacement levels of leptin.

Scientists at the Howard Hughes Medical Institute and The Rockefeller University in collaboration with investigators at Yale University have found that leptin --- a hormone found in fat tissue and ...