The anti-obesity medication tirzepatide, marketed as Mounjaro for diabetes and Zepbound for obesity, reduced ...

Cutting a single amino acid from the diet caused rapid, drastic weight loss in mice by converting white fat into ...

Depression wears many faces—some sad, some silent. But could it also wear a shape? In two new studies exploring the hidden links between body composition and mental health, researchers are uncovering ...

Synopsis Neuronal deficiency of LGR4 improves hypothalamic leptin sensitivity via suppression of β- catenin signaling, which subsequently increases energy expenditure and decreases food intake, thus ...

The hormone leptin helps you feel full. You don’t get it from food, but a poor diet or extra pounds may make it less effective.

Mouse study published in Science Translational Medicine suggests an old approach to obesity, the leptin hormone, could improve efficacy of GLP-1 drugs.

A pharmacist discusses supplements that affect leptin levelsMedically reviewed by Allison Herries, RDNMedically reviewed by Allison Herries, RDNLeptin is a hormone that is derived from fat cells. It ...

WebMD explains what the leptin hormone is, how it affects weight, and whether leptin supplements are safe or effective.

Is coconut oil healthy? A study found that it disrupted mice’s ability to use leptin and insulin, two critical hormones, and as a result, may lead to diabetes and obesity.

A MetS rat model was established in 8‐week‐old Wistar rats by a 12‐week high‐fat diet. MetS rats exhibited increased leptin secretion from EAT, cardiac hypertrophy, and diastolic dysfunction with ...

However, studies have found that there is no leptin receptor expression or very little expression in ARC nucleus GnRH neurons (26). Therefore, leptin cannot directly act on GnRH neurons, but it is ...

This work describes a mouse model of a human mitofusin 2- related lipodystrophy, generated by knockin of Mfn2 R707W, and reports adipocyte-specific effects involving activation of a cellular ...