B7-33 is a synthetic peptide derived from the relaxin protein family, specifically designed to interact with the relaxin ...

Scientists have developed a technique that aligns stem cells into a single sheet, resulting in a marked increase in the secretion of signaling proteins which help repair tissue and regulate the immune ...

The UAB researchers showed that TREM2 — which stands for triggering receptors expressed on myeloid cells 2 — is predominantly ...

Preclinical study results provide a comprehensive transcriptomic characterization of regenerative wound repair in the oral mucosa.

The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved ...

Background Idiopathic pulmonary fibrosis (IPF) is characterised by damage to the epithelial layer, closely associated with the alveolar basement membrane (BM). We aimed to investigate how type IV ...

Researchers at Baylor College of Medicine and collaborating institutions have uncovered a key molecular player that is involved in lung repair and in the development of pulmonary fibrosis, a common ...

Tissue samples collected at various time points were analyzed for fibrosis-related gene expression changes and collagen content. Low (1.5 U/kg) and high-dose (2.5 U/kg) bleomycin instillations alone ...

So, TREM2 in liver macrophages is critical for promoting tissue repair and preventing excessive fibrosis, suggesting its potential as a therapeutic target.

Idiopathic pulmonary fibrosis (IPF) is a rare condition where the lungs become scarred, making it hard to breathe. The cause of the disease is unknown, which is why it is called ‘idiopathic.’ So far, ...

Liver fibrosis is a buildup of scar tissue in the liver, which can occur when the liver tries to repair and replace cells due to inflammation or damage. Liver fibrosis does not always present ...