To study the mutually exclusive expression of odorant receptor (OR) genes, we generated transgenic mice that carried the murine OR gene MOR28. Expression of the transgene and the endogenous MOR28 ...

Research led by the National Institute of Biological Sciences in Beijing has discovered that switching on a single dormant ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

The study provides a potential framework for dissecting mechanisms underpinning the failure of regeneration in other organs ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...

Written by None for Quiver Quantitative -> XPro™ treatment post-TBI shows promise in reducing Alzheimer’s-like pathology in transgenic mice, improving neurological outcomes. Quiver AI Summary ...

University of Texas Southwestern Medical Center scientists found that activating fibroblast growth factor 21 (FGF21) ...

Studies in human cell lines and transgenic mouse models show that non-receptor tyrosine-protein kinase TYK2 phosphorylates tau at Tyr29 and thereby promotes its stabilization and accumulation.

hfCas13d-mediated knockdown of CA2 and AQP1 lowers IOP in wild-type mice. A) A total of 2 × 1010 genome copies of different AAV serotypes encoding GFP were injected into the vitreous cavity of ...

The bacteriophage P1 Cre/ lox P system has become a powerful tool for in vivo manipulation of the genomes of transgenic mice. Although in vitro studies have shown that Cre can catalyze recombination ...