Enhanced ADCC (antibody-dependent cellular cytotoxicity): The engineered dimeric IgG1 backbone not only delivers payload but actively engages the immune system to kill tumor cells directly.

TAIPEI, Taiwan, June 06, 2025 (GLOBE NEWSWIRE) -- OBI Pharma, Inc. (OBI), a clinical-stage global oncology company specialized in the development of novel cancer therapies such as antibody-drug ...

Affinity chromatography remains one of the main methods for purifying antibodies, enabling high specificity and yield. Whether working with recombinant monoclonal antibodies or polyclonal antibodies ...

In line with this, a recombinant antibody with increased PC affinity identified by phage display and cloned onto a human IgG1 backbone inhibited oxLDL uptake and the subsequent production of CCL2 ...

This repository contains the antibody-antigen test cases, with unbound and bound structures, for Docking Benchmark 5.5. This dataset is a major update of Docking Benchmark 5.0, which was released in ...

Gold nanoparticles (AuNPs) functionalized with antibodies have the potential to improve biosensing technology because of the unique optical properties of AuNPs and the specificity of antibody–antigen ...

Results Prominent reactivity against a 56 kDa protein was detected in human H69 cholangiocyte lysates exposed to sera of nine patients with IAC/AIP. Affinity purification and mass spectrometry ...

Therapeutic antibodies are prone to degradation via a variety of pathways during each stage of the manufacturing process. Hence, a low-cost, rapid, and broadly applicable tool that is able to identify ...

These included six AChR-antibody-negative samples for both L- and F-CBA, seven F-CBA−/L-CBA+, and eight double-positive sera (L- and F-CBA), in addition to several negative controls. The in-house ...