Protein complementarity may offer new insights into autoimmune diseases ... The patients in the study had a particularly aggressive form of vasculitis caused by ANCAs against a protein called PR3.

Protein Complementarity May Offer New Insights Into Autoimmune Diseases Date: August 14, 2008 Source: American Society of Nephrology Summary: The discovery of "complementary" antibodies against ...

The results showed autoantibodies to a complementary protein that, to the researchers’ surprise, turned out to be plasminogena protein. In the research, 22% of the patients with PR3 ANCA ...

Engineering protein thermostability using a generic activity-independent biophysical screen inside the cell. Nat. Commun. 4:2901 doi: 10.1038/ncomms3901 (2013).

The discovery of "complementary" antibodies against plasminogen in patients with blood vessel inflammation caused by anti-neutrophil cytoplasmic autoantibodies (ANCAs) may lead to new approaches ...