As Synedgen's Chief Executive Officer and Chief Scientific Officer, Dr. Saward will continue to lead the company to deliver on the successful partnership with Biomedical Advanced Research Agency (BARD ...

The interaction of viruses with cells is mediated by the glycocalyx, a ubiquitous cell coating layer. Here, we present a study of the effects of the cellular glycocalyx, a complex outer cell structure ...

The study looked at a drug called spironolactone. It’s normally used to treat high blood pressure, but it’s now showing ...

In people with diabetes, this layer is often damaged, which leads to kidney problems over time. Spironolactone seems to protect the glycocalyx from harm, helping the kidneys function better for ...

Ulcerative colitis (UC) and Crohn’s disease (CD) (collectively termed inflammatory bowel disease (IBD)) are complex disorders reflected by wide variation in clinical practice. These guidelines, ...

These effects are primarily mediated by mechanosignal transduction through focal adhesions, glycocalyx, cell-cell junctions, ion channels, and Notch receptors. Such mechanical signaling can upregulate ...

The glycocalyx is a carbohydrate-rich layer that lines the endothelial surface, providing a protective barrier against mechanical forces and maintaining vascular homeostasis. 16 The flushing catheter ...

Hydrogels have emerged as a promising class of extracellular matrix (ECM)-mimicking materials in regenerative medicine. Here, we briefly describe current state-of-the-art of ECM-mimicking hydrogels, ...