In this study, scientists wanted to understand exactly how spironolactone protects the kidneys. They discovered that the drug ...

The study looked at a drug called spironolactone. It’s normally used to treat high blood pressure, but it’s now showing ...

These effects are primarily mediated by mechanosignal transduction through focal adhesions, glycocalyx, cell-cell junctions, ion channels, and Notch receptors. Such mechanical signaling can upregulate ...