It is active against Neisseria gonorrhoeae and Gram‐positive cocci, and currently in phase 3 clinical trials for the treatment of uncomplicated gonorrhoea. Zoliflodacin has a distinct binding site in ...

This important study fills an gap in our knowledge of the evolution of GPCRs in holozoans, as well as the phylogeny of associated signaling pathway components such as G proteins, GRKs, and RIC8 ...

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Here, we describe our efforts that led to the identification of 5-amino-4-quinolone 111 with exceptionally potent Gram-positive activity with minimum inhibitory concentrations (MICs) ≤0.06 μg/mL ...

Bioinformatic identification of differentially expressed genes associated with prognosis of locally advanced lymph node-positive prostate cancer Anna V. Kudryavtseva , Elena N. Lukyanova ...