Taylor dispersion analysis, also referred to as TDA, is an orthogonal method used for stability and sizing analyses of biomolecules in solution. Research has shown that hydrodynamic radius (Rh ...

The hydrodynamic radius exhibits a sigmoid relationship as a function of temperature for all antibody concentrations at pH 9.5, showing little change in the midpoint with concentration. Reversible ...

Protein size analysis and any other research area involving hydrodynamic radius involves a similar calculation using an additional factor of two. When polymer size is under study, it must be noted ...

Changes in MW, hydrodynamic and r.m.s. radius, as well as protein conformation, are observed when comparing the results obtained under different separation conditions. Advantages and limitations ...

Dynamic light scattering (DLS) measures fluctuations in the intensity of scattered light, caused by the Brownian motion of particles. By analysing these fluctuations, DLS can determine the diffusion ...

DLS provides rapid measurements of hydrodynamic radius (Rh), degree of polydispersity, temperature of aggregation onset, and colloidal stability. Formulation screening with DLS helps developers ...