Induction of IRF-1 gene expression following stimulation by IFN-γ is dependent on the JAK/STAT signalling pathway and genes downstream of IRF-1 in this pathway include, IFN-β (Fujita et al ...

By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of ...

Most Toll-like receptors (TLRs) are believed to act as homodimers, although heterodimers do exist. The Toll interleukin-1 receptor (TIR) domain adaptors, MyD88, MAL/TIRAP, TRAM, and TRIF, also ...

Scientists discover a new signaling pathway and design a novel drug for liver fibrosis. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2024 / 04 / 240426110048.htm ...

Human exposure to toxic particles drives various diseases. Examples include gout, an acute arthritis driven by monosodium urate crystals, or MSUc; CPPD disease, another inflammatory joint disease ...

Research has identified the first inter-species signaling pathway between an arthropod parasite and host, where molecules in the blood of a host animal triggers the immunity and development of a ...

A rare cell in the lining of lungs is fundamental to the organ-wide response necessary to repair damage from toxins like ...