Researchers investigated the complement component 1q (C1q) binding and subsequent complement activation by neutralizing antibodies (nAbs) produced following COVID-19 vaccination.

In this article, ACROBiosystems discusses how the complement cascade and it's various components could potentially be leveraged for therapeutic potential in COVID-19, cancer and general inflammation.

Cryoglobulins containing IgG, IgM and complement have been described in the serums of patients with SLE. 6 Such cryoglobulins have been found to have an anticomplementary effect, 8 and ...

This antibody, which was of the IgG class, fixed complement, ... N. L. Activation of plasma kinin system by antigen–antibody aggregates. I. Generation of permeability factor in guinea pig serum.

IgG antibodies activate blood platelets and contribute to the severity of anaphylaxis. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2018 / 05 / 180515105707.htm ...

IgG antibodies activate blood platelets and contribute to the severity of anaphylaxis. Institut Pasteur. Journal Science Immunology DOI 10.1126/sciimmunol.aan5997 ...

Researchers present structures of ZIKV NS1 in complex with five human antibodies at 2.6–2.9 Å resolution. The structural and biochemical results elucidate the correlation between epitope ...

Additionally, ARO-CFB may have clinical applications in non-renal diseases involving complement activation. About the AROCFB-1001 Phase 1/2 Study. AROCFB-1001 (NCT06209177) ...