Noninvasive brain stimulation techniques, including transcranial direct current stimulation, are effective nonpharmacologic treatments for insomnia.

Researchers found a way to implement cognitive behavioral therapy for insomnia (CBT-I) at scale, using a proprietary software called COAST, and with good early results to boot.

Yet greater awareness of sleep deprivation’s consequences hasn’t translated into a better-rested populace. Data from the CDC ...

Insomnia Severity Index (ISI) score was reduced, with one and a half as many patients treated with daridorexant vs placebo improving by ≥6 units, the threshold of clinical relevance. The impact of ...

Secondary outcomes reinforced the primary findings. The Insomnia Severity Index (ISI) scores decreased more significantly in the taVNS group, with a mean difference of −4.7 points at week 8.

Modius Sleep lowered Insomnia Severity Index by 24.5% in the intention-to-treat cohort and 29.4% in the PP cohort, compared with 17.1% and 18% in the sham group, respectively.

Key findings After four weeks of treatment, nearly half of the participants (45%) achieved an Insomnia Severity Index (ISI) score below 7, indicating a clinically significant resolution of insomnia.

The topline readout found that chloral hydrate significantly improved insomnia symptoms in adults with severe insomnia. The primary efficacy endpoint, change in Insomnia Severity Index (ISI) score ...

Results were measured according to the Insomnia Severity Index (ISI), a seven-item questionnaire that assesses subjective sleep quality and the severity of insomnia symptoms.

One group was assigned 16 weeks of moderate exercise, the other eight weeks of relaxation training followed by eight weeks of CBTi and exercise. Results were measured according to the Insomnia ...

At baseline, patients had an Insomnia Severity Index (ISI) score of 10 or greater, with sleep disturbances on 3 or more nights per week for 3 or more months. Insomnia severity was considered mild ...

1. In patients with acute insomnia, an online behavioral self-help intervention was effective in reducing insomnia severity within one week. 2. Patients with acute insomnia provided with a two-page ...