Ion exchange (IEX) chromatography is a technique that is commonly used in biomolecule purification. It involves the separation of molecules on the basis of their charge. Skip to content.

Chromatography remains a cornerstone in the purification of proteins, ... and ion exchange, ... underscoring the potential of machine learning techniques for real-time process optimisation [3]. ...

In literature, the terms “ion exchange chromatography” and “ ion chromatography ” (IC) are often used interchangeably, thanks to the wide use of IEX, and refer to the separation of polar or ionic ...

A focus will be done on ion-exchange chromatography and main features of the thermodynamic model. Major applications of ion-exchange chromatography will also be presented, spanning across the ...

There is a natural migration in the use Ion Pair Reversed-phase (IPRP) for Oligonucleotide [ON] characterisation when the ability of interfacing with mass spectroscopy [MS] is required.

Ion exchange chromatography. One of the most popular methods for separating proteins is ion exchange chromatography. It separates proteins in a sample based on charge.

Figure 2: A schematic representation of the diffusive pores in beaded chroma-tography and convective pores in membrane chromatography. Pleated ion-exchange membranes possess large convective pores, ...

As such, sorbitol is to hydrogen bond chromatography as what salts are to ion exchange chromatography. A sorbitol solution of 200 mM reduced binding strength for all tested samples by about half.

IN the technique of ion-exchange chromatography, the order in which compounds are eluted from a column depends basically upon differences in their ionization constants; but other factors modify ...