Cancer fighting T-cells, the immune system's primary enforcers, are scarce in the rare kidney cancer called chromophobe renal cell carcinoma (ChRCC) and those that are present are indifferent to the ...

Dysregulation of the alternative complement pathway, hallmarked by isolated reduction of the serum C3 fraction, is now recognized as an additional feature of lupus nephritis. Persistent, isolated low ...

Achieving sustained complete renal response (sCR) is both a realistic and essential goal for patients with lupus nephritis (LN), markedly improving long-term kidney survival and overall patient ...

Microscopic colitis is a chronic inflammatory condition of the colon characterized by watery diarrhea, normal or near-normal endoscopic findings, and distinctive histologic features. First recognized ...

Background We employed urine proteomics to define the molecular signatures associated with the histological features quantified by the NIH activity and chronicity indices.Methods We employed urine ...

Objective To investigate second kidney biopsy as predictor of end-stage kidney disease (ESKD) in active lupus nephritis (LN).Methods Patients with biopsy-proven LN (International Society of Nephrology ...

MASLD was more common in White patients vs Black patients (31% vs 8%). Black patients were more likely than White patients to have hypertension (68% vs 56%) and chronic kidney disease (17% vs 8%), ...

MVI is a key histologic feature of AMR and higher MVI scores strongly correlate with reduced kidney allograft survival rates. 2 ...

With long-term survival increasingly achievable for patients with multiple myeloma, treatment strategies are evolving to ...

Diagnosing these conditions can be challenging due to overlapping symptoms and histologic features. The cause can typically be determined with a kidney biopsy, however, few patients undergo that ...

Predicting clinical endpoints and visual changes with quality-weighted tissue-based renal histological features Ka Ho Tam 1* Maria F. Soares 2 Jesper Kers 3,4,5 Edward J. Sharples 6 Rutger J. Ploeg ...