The human kidney is a masterclass in biological engineering. Responsible for filtering approximately 50 gallons of blood ...

Chronic kidney disease (CKD) is a global health threat, affecting over 10% of the world population, including an estimated 37 million Americans. Importantly, glomerular diseases account for 70% of all ...

Terminal disease readouts from NZB/W mice at 48–50 days following IFNa adenovirus delivery (n = 8–10/group). Total kidney histology scores include assessments of glomerular, tubular, and interstitial ...

With tumor progression metabolism of the body is disturbed and toxic metabolites, entering the blood, can affect the structure of organs distant from tumor growth. The kidneys are one of the main ...

The effects of treatment on survival, proteinuria, kidney histology, glomerular IgG deposition, cytokine-secreting cells, and circulating cytokines were measured.Results Afimetoran treatment resulted ...

Vanderbilt researchers created the first high-res lipid atlas of the human kidney, mapping over 100,000 functional tissue units across 29 donors. This atlas is the most comprehensive of its kind ...

GALNT11 (Galnt11 in mice) encodes a member of the large glycosyltransferase family responsible for initiating mucin-type O-glycosylation of secreted and membrane-bound proteins (6, 7). The ortholog of ...

In the kidney, ≈80% to 90% of NHE3 is expressed in the proximal tubules alone. 34, 35 NHE3 is the most important Na + /H + exchanger or antiporter in the proximal tubules and is directly and ...